BioGPS Featured Article – Constrained transcription factor spacing is prevalent and important for transcriptional control of mouse blood cells | The Su Lab

BioGPS Featured Article – Constrained transcription factor spacing is prevalent and important for transcriptional control of mouse blood cells | The Su Lab.

Here’s some quick background for this week’s BioGPS featured article. transcription factors play an important role in gene expression, but there’s still a lot to be learned with regards to how they actually work.

The authors of this paper chose to use mouse haematopoiesis as a model for learning more about how transcription factors work because the spacing between DNA binding motifs has been reported to be functionally important in mouse haematopoiesis.

Learn more about what the authors found with the BioGPS Featured Article post or check out the open-access article.

Finally, checkout the tools the authors behind this paper have worked on: CODEX (formerly HAEMCODE)

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