Happy New Year! May you enjoy new relationships and build new bridges in your personal network. Speaking of networks, this week’s BioGPS featured article looks at protein interactions and metabolic networks to uncover bridge proteins in bile acid metabolism which may have prognostic potential for colorectal cancer.
The researchers defined a new metric, “Bridgeness” (which represent the degrees of connection between sensors and enzymes) in their network-based approach for finding prognostic markers in colorectal cancer. Although it’s too early to say whether or not this research will lead to improved prognostic tools, it’s still very exciting, considering the current methods for colorectal cancer screening. Sorry, but endoscopies or colonoscopies for screening purposes are such a pain in the butt!
Think their research is cool? See the BioGPS featured article for the researcher’s perspective/insight on their work here, or read the original research article. You can also comment on their open access paper here.